Reactors and bioreactors are the heart of advanced chemical, biotechnological, and fermentation processes. We offer devices designed for the highest standards of GMP (Good Manufacturing Practice) and sterility, ideal for synthesizing Active Pharmaceutical Ingredients (API), conducting precise reactions, and for cell and microbiological cultures in pharmaceutical and nutraceutical production.

Our reactors and bioreactors have been designed with the highest process standards in mind, especially in the pharmaceutical, biotechnological, and fine chemical industries.

Main
Technical
Features:

1. Design and Heat Exchange

  • Process tank equipped with a heating-cooling jacket or half-pipe coils, ensuring effective temperature control during reactions and fermentation.
  • Capability for operation under pressure and vacuum conditions, with thermal insulation to limit energy loss.
  • Construction adapted to the requirements of chemical, biotechnological, and pharmaceutical processes.

2. Mixing System

  • Mechanical or magnetic drive – depending on sterility requirements and the type of medium.
  • Adjustable rotational speed through the use of an inverter allows for process optimization.
  • Interchangeable types of stirrers (turbine, anchor, propeller, gate) selected based on the nature of the mixture and product viscosity.

3. Automation and Process Control

  • An integrated PID control system ensures precise regulation of temperature, pH, and dissolved oxygen (DO) level.
  • An HMI operator panel allows for monitoring and recording of key parameters: batch and jacket temperature, pressure, mixing speed, and pH.
  • Capability for integration with supervisory control systems (SCADA, MES) and remote access to process data.

4. Safety and Process Control

  • The use of safety valves, level, pressure, and temperature sensors, as well as process media detection systems, guarantees safe operation of the device.
  • Safety systems compliant with applicable ATEX, PED, or GMP standards (depending on configuration).

5. Hygiene and Execution

  • Internal surfaces polished to a roughness of , meeting GMP and EHEDG requirements.
  • Capability for full IQ/OQ validation and qualification, ensuring compliance with pharmaceutical procedures.
  • Optional CIP/SIP (Clean / Sterilize In Place) system for automatic washing and sterilization without component disassembly.

6. Seals and Drive

  • Double mechanical seal with barrier pressure control system or magnetic sealing for aseptic processes.
  • Motor drive with a high energy efficiency class, adapted for continuous operation.

7. Scalability and Configuration

  • Available capacities from 50 to 20,000 liters, with the possibility of custom manufacturing to individual process requirements.
  • Constructions in standing, modular, or mobile versions, adapted to the plant’s infrastructure.